---
title: "Synthesize Bio MCP integration for LuumenAI"
url: "https://www.luumen.ai/integrations/synthesize-bio-mcp/"
entity: SoftwareIntegration
category: "AI & automation"
audience: "SRE, DevOps, platform engineering, IT operations"
---

# Synthesize Bio MCP integration for LuumenAI

Start and track gene-expression analyses from a plain-language experiment brief

## What LuumenAI can do with Synthesize Bio MCP

LuumenAI connects to Synthesize Bio MCP with OAuth 2.0 and exposes 5 tools (4 read-only · 1 destructive). For connected tools, admins configure which actions may run automatically and which require approval, within the access granted to the user.

## Key facts

- Authentication: OAuth 2.0
- Tools available: 5 tools (4 read-only · 1 destructive)
- Deployment: scoped as part of your Pilot, Platform, or Managed rollout
- Category: AI & automation

## About Synthesize Bio MCP with LuumenAI

Connect Synthesize Bio and Luumen can turn a written experiment description into structured sample groups, check them against the controlled ontology, and start a bulk or single-cell differential expression run. It polls job status, and hands back a presigned URL for the raw counts data when results are ready. Authentication is handled over OAuth with dynamic client registration.

## Example tools

Read-only (4 in total):

- `SYNTHESIZE_BIO_MCP_GET_ANALYSIS_RESULTS` — Polls the status of a gene expression analysis.
- `SYNTHESIZE_BIO_MCP_GET_COUNTS_DATA_URL` — Returns a presigned S3 URL to download the raw gene expression counts data (JSON) produced by a completed or in-progress analysis job.
- `SYNTHESIZE_BIO_MCP_GET_METADATA_SCHEMA` — Returns the structured-metadata schema used to turn a natural-language experiment description into sample groups.
- `SYNTHESIZE_BIO_MCP_RESOLVE_SAMPLE_METADATA` — Deterministically harmonizes already-structured sample `groups` to Synthesize Bio's controlled ontology vocabulary.

Write and destructive (1 in total, subject to configured approval policy):

- `SYNTHESIZE_BIO_MCP_ANALYZE_GENE_EXPRESSION` — Starts a differential gene expression analysis using Synthesize Bio's AI platform.

## Frequently asked questions

### How does LuumenAI connect to Synthesize Bio MCP?

Authorize once with OAuth 2.0. Luumen lists the scopes each action needs before you approve the connection, and credentials never appear in the chat.

### Can LuumenAI change things in Synthesize Bio MCP on its own?

For connected tools, admins configure which actions may run automatically and which require approval, within the access granted to the user.

### Is there an audit trail?

Every call to Synthesize Bio MCP — read or write, approved or declined — is recorded with the actor, the input, and the result.

Full page: https://www.luumen.ai/integrations/synthesize-bio-mcp/